Sentence examples for extensive induction of from inspiring English sources

Importantly, both compounds led to the same rapid and extensive induction of apoptosis as observed with Cisplatin (Figure 4A; right panel).

However, the co-expression of CLOCK and BMAL1 with either PER1 or PER2 resulted in an extensive induction of Per2::luc, while subtle inductions by PER1 and PER2 were observed (Figure 5B, middle panel).

We used hh-Gal4>UAS-hid UAS-p35 to generate undead cells in the posterior compartment and extensive induction of cell death in the anterior compartment.

Therefore, the increase in serum IFNγ levels that we detected could potentially result in a more extensive induction of apoptosis in the CD4+/Vβ8+ T cell population.

Subsequently, the ICLs physically impede the progress of the replication fork and transcriptional machinery causing replication stress and blocked transcription process, leading to activation of the intra-S checkpoint, and if the lesions are too extensive, induction of cell death [ 3].

43– 45 A study by Kaneda et al. suggested that the overexpression of Dnmts by latent proteins and epigenomic changes, such as 3-D conformational changes and histone modifications, might be involved in the extensive induction of methylation in Epstein Barr virus-associated cancer.

The unique sensitivity of TGCT cells to Cisplatin has also been linked to an extensive and rapid induction of apoptosis and to a reduced ability to induce cell cycle arrest, probably caused by altered functionality of the p53 pathway in these cells [12].

The reduction of R2* was associated with the induction of extensive central necrosis induced by ZD6126, as measured by histology.

Mammary epithelial expression of mutant PyV mT decoupled from the PI-3K pathway results in the induction of extensive mammary epithelial hyperplasias [ 15].

These findings suggested that the marked inhibitory effects of β43 63 in the tubule formation assay were not due to induction of extensive EC death.

Intravenous injection of one such agent, JS-K, into mice bearing subcutaneously implanted multiple myeloma tumors on the flank, resulted in an impressive inhibition of tumor growth and induction of extensive apoptosis throughout the tumor.