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A conventionally constructed but engrossing account of Kozmic Blues queen Janis Joplin's tragically condensed rise and fall, it injects fresh perspective into a known downward spiral via extensive incorporation of Joplin's personal correspondence – liltingly voiced by Cat Power.
Extensive incorporation of analytic information about singular integral kernels and on-the-fly computation of nearly singular quadrature rules allow for very high achievable accuracy, also in the evaluation of fields close to the boundary of the computational domain.
IP-CHA granules consist of a porous sintered body made of hydroxyapatite ceramics and have a unique pore structure, thus they undergo extensive incorporation into host bone more rapidly than conventional interconnected porous hydroxyapatite ceramics (C-CHA) [ 5, 6].
In the literature the exact mechanisms are controversially discussed: one strand stays single-stranded during replication in the strand-displacement model [ 25], or is subject to extensive incorporation of ribonucleotides in the strand-coupled model [ 26].
Although it is not clear how DHA induces mitochondrial ROS in PC3 and DU145 cells, DHA supplementation has been shown to result in its extensive incorporation into mitochondrial membrane phospholipids and to enhance mitochondrial lipid oxidation and ROS generation, leading to mitochondrial dysfunction [ 39, 40].
In the presence of 0.1 mM L-homocysteine all of the cell lines synthesize macromolecules from [5-14C]methyltetrahydrofolic aciduringng a 24 h period, and the cell line with the highest methionine requirement shows the most extensive incorporation of radiolabel into DNA and RNA, both in depleted medium and in medium containing 6.7 microM L-methionine.
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Extensive nucleotide incorporation assays by HCV NS5B RNA-dependent RNA polymerase showed that 44a and 45a can serve as chain terminators, whereas compounds 43a, 46a, and 47a are competitive inhibitors with ATP.
Although we do not at present have an explanation for this, it is unlikely that this discrepancy is due to the use of different somatic cells or to interspecies incompatibilities as we observed extensive BrdU incorporation using both human and mouse fibroblasts.
Recoupling experiments, originally designed for applications in spin-pair labeled samples, have been revised in recent years for applications in samples with extensive or uniform incorporation of isotopic labels.
Whereas control embryos display extensive nuclear BrdU incorporation throughout the embryo, SpRunt-1 morphants do not (Fig. 1A), indicating that SpRunt-1 expression supports progression of the cell cycle through S-phase in late blastula stage embryos.
The data underwent extensive validation before incorporation into the CMPD.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com