While speed itself is not an overriding optimality criterion, rapid analyses will permit robust and extensive exploration of parameter space.
However, a more comprehensive mathematical representation of the biological processes involved comes at the expense of an increased number of free parameters, making more difficult an extensive exploration of the parameter space.
As a preliminary step, an extensive exploration of the parameter space was carried out in order to determine which parameter combinations allow for long-term coexistence of pathogens and hosts.
Estimates for the rate constants in the reaction cycle and the internal strain energy are obtained by a computational comparison scheme involving an extensive exploration of the large parameter space.
This study uses previous research as a point of departure, and builds on this through a number of improvements including: (1) time-based modelling (2) more extensive exploration of uncertainty around input parameters and assumptions, (3) more conservative assumptions around changes in PA over time that underestimated benefits of PA and (4) use of meta-analysed effectiveness data.
This study builds on the current limited economic literature through a number of improvements including: (1) time-based modelling, (2) more extensive exploration of uncertainty around input parameters and assumptions, (3) more conservative assumptions around changes in PA over time and (4) use of meta-analysed effectiveness data.
Nevertheless, we have produced respectable assemblies after extensive exploration of different assemblers and assembly parameters.
The variable z is shown in Fig. 1, with the different spatial variation patterns defined using z, z a, z b shown in Fig. 2. Parameter variation in both model parameters and spatial variations within individual simulations collectively provide an extensive exploration of the quantitative effects of spatial variation in a specific pathway.
Extensive exploration of the operational window of the ITER divertor has lead to the emergence of simple scalings of the divertor plasma parameters with input power and plasma density, which are used here to make an educated guess on the divertor performance in a commercial reactor.
After a short stay in Cuba, Humboldt and Bonpland returned to South America for an extensive exploration of the Andes.
