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The various arms of the vertebrate immune response are interdependent, and the upregulation of one arm has extensive effects on the expression of other immune modes; the TH1/TH2 inhibitory dicotomy is a well known example of this effect.
Accidental releases of flammable gases may lead to major fires with extensive effects on the surroundings, mainly due to the intense thermal load emissions.
It has been demonstrated that PNS have extensive effects on the cardiovascular system, including inhibition of platelet aggregation, increasing blood flow, improving left ventricular diastolic function in hypertensive patients and anti-inflammatory effect.
Not only does it exerts extensive effects on fatty acid metabolism (Clark, 1981, Nunn et al., 1983, Hughes et al., 1988), but also regulates acetate metabolism (iclR) (Gui et al., 1996, Maloy & Nunn, 1981) and stress response (uspA) (Farewell et al., 1998).
Microarray studies suggest that epigenetic factors can have extensive effects on levels of gene expression [7].
Jitter had more extensive effects on the trajectory classifiers, especially at small timescales.
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We show the extensive effects of smoking on peripheral mononuclear cell DNA methylation on pathways involved in coagulation, CNS and immune function.
Given the extensive effects of acetylation/deacetylation on gene regulation, the observed HDAC hyperactivation would likely result in significantly altered rd1 gene transcription, which matches with previous microarray data.
A huge number of transcriptomic investigations have shown the extensive effects of AM colonization on host metabolism [ 51, 54] and identified a core set of genes that respond to mycorrhization for all tested plants, fungi, and organs.
In contrast to the extensive effects of adult-onset hyperthyroidism on expression of the Shh cascade, hypothyroidism in adulthood resulted in a spatially restricted and selective down-regulation of Smo expression within the DG.
We have shown that changing the acidity of the solution to extracted dye from B. vulgaris had an extensive effect on the absorption spectra.
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