Sentence examples for extensive disruption to from inspiring English sources

The resulting health problems can continue for many years and cause extensive disruption to the personal and family life of the victim.

A CalMac spokesman said: "The severe weather experienced across the west coast today has caused extensive disruption to our services across the whole network.

Speaking to BBC London 94.9, Ms Powell said: "It is the scale of the work we are objecting to which is going to lead to about two years of extensive disruption to Hampstead Heath, permanently disfiguring the natural setting... which we have argued won't resolve the problem the City of London has identified".

These same treatments also disrupted nuclei, which normally polarize posteriorly in a PCP-dependent manner (Jiang et al., 2005), indicating an extensive disruption to the normal polarity of notochord cells.

European colonisation created extensive disruption to Aboriginal society including dispossession of traditional lands, movement of people, removal of children, loss of traditional lifestyle and introduction of tobacco and alcohol[ 49].

The previously reported CA1-diamine analog and its corresponding hydrochloride salt (8 and 10, respectively) caused extensive disruption (at a concentration of 1.0 μM) of human umbilical vein endothelial cells growing in a two-dimensional tubular network on matrigel.

"This extensive disruption has led to us needing to re-start services with another train to avoid them being completely cancelled.

This led to extensive disruption of the city's water supply, electricity distribution and generation networks, wastewater networks, ground and air transportation networks, and necessitated a major ash clean-up operation within the town (Wilson et al. [2012c]).

This narrows the portion of ActA responsible for facilitating more extensive disruption of the phagosome to less than 15 amino acids.

Reaming of the medullary canal of the femur for autologous bone graft collection using the reamer-irrigator-aspirator creates a cavity that fills with haematoma due to the extensive disruption of the medullary arterial vasculature.

Calcium overload can induce: (1) activation of calpains, leading to more extensive disruption of cytoskeleton components, (2) activation of calcium-dependent phospholipases, and disruption of membrane permeability, (3) Mitochondrial permeabilization and bioenergetics collapse.