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In the studies performed so far, relatively extensive differences were detected, even within different tumours originating from the uterus of the same patient [ 36, 37].
After evaluating intergroup differences in an exploratory manner, extensive differences were not evident between the UCLP and BCLP groups.
Extensive differences were observed in 5′ and 3′ ends, and Figure 2 summarizes the number of genes with differential ends.
At the V stage, during which young developing maize leaves efficiently assimilate CO2 through the C4 photosynthetic pathway and inorganic N for amino acid and protein synthesis [ 16], extensive differences were observed in metabolite accumulation between the two GS mutants in comparison to the WT (Additional file 1: Table S1).
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However, no significant and extensive difference was detected among these three regions, which did not support the climate adaptation hypothesis but preferred random genetic drift to be the main factor in shaping the current landscape of human mtDNA, at least those from Asian and Oceanian regions.
In prior work and in this study, extensive epigenetic differences were observed between adjacent-normal and DCIS tissues, confirming that pre-invasive DCIS lesions harbor a high degree of disruption in the methylation patterning of ductal epithelial cells [ 24].
Extensive interstrain differences are observed among LPS biosynthetic gene clusters of animal pathogenic bacteria [ 2].
Intraoperative differences were extensive.
Stage-specific differences were extensive in V. dahliae at the gene regulatory level during MS development.
As expected, striatal transcriptome differences were far more extensive between the independently derived progenitor strains than between the quasi-congenic strains and their background partner, B6By.
Pairwise differences were even more extensive: 77% of the measured transcriptome exhibited a significant difference among at least two strains measured in a common copper environment, whereas 67% exhibited a response to copper across the reaction norm of at least one strain.
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