Sentence examples for extensive clinical application of from inspiring English sources

In summary, the development and extensive clinical application of long-term antihormonal therapy [ 11] has had consequences for the patient with the development of antihormonal drug resistance in some breast cancers [ 31].

Despite of extensive clinical applications of TCM formulae, knowledge about their pharmacological activities, mechanisms of action and cellular targets remains limited.

The imaging of the SST subtype 2 (SST2) overexpressing NETs has been developed and has had extensive clinical applications for almost two decades [ 20].

Further investigation is still needed into its extensive clinical application in neurodegenerative diseases and tumoural pathological conditions.

This is impractical for extensive clinical application as it confines the tissue engineering process to an individual therapy and thereby restricts the possible future industrialization and standardization of tissue-engineered products.

Large randomized studies are still needed before extensive clinical application in this condition.

However, its extensive clinical applications have been limited because of poor aqueous solubility, short half-life time and side effects.

Targeting the immune response in the periphery has led to a number of therapies for MS, however the serious side effects of the drugs have prevented their extensive clinical applications [2].

Adenovirus-mediated gene transfer of IFN- β was also examined for the clinical feasibility (Yoshida et al, 2004), but type I IFNs produced a number of adverse effects (Dusheiko, 1997), which may limit the extensive clinical applications.

The high dose required for clinical application of MSCs entails extensive in vitro expansion, which has been shown to cause enlargement of cells [ 58].

However, in future movements towards the clinical application of our research a more extensive and exhaustive demonstration that the technique used is aseptic would be necessary.