Sentence examples for extensive changes of from inspiring English sources

Extensive changes of higher order chromatin arrangements can be observed during prometaphase, terminal cell differentiation and cellular senescence.

Extensive changes of a huge amount of data at neighbouring locations may indicate that the changes have been coordinated in some way.

Since ATRA acts throughout events that require extensive changes of nuclear architecture and activity and considering that Vav1 accumulates inside the nuclear compartment of differentiating APL-derived cells, the possible role of this protein in modulating the nuclear proteome was investigated.

Analysis of TCR repertoires in mice bearing advanced tumors shows extensive changes of effector and Treg cells isolated from various anatomical locations.

Furthermore, as the environmental pH falls due to acid production by S. mutans and glucans are synthesized, the pathways required for optimal metabolism and survival of S. mutans in biofilms may be switched leading to extensive changes of the gene expression profile at 30 h of biofilms formation when compared to other time-points.

The tubules showed extensive changes of tubular epithelial injury including tubulorrhexis and focal regeneration.

Now, as Lt. Gov. David A. Paterson prepares to succeed Mr. Spitzer, Republicans and Democrats alike are predicting an equally extensive change of atmosphere and, for better or worse, a return to comity between the governor and the Legislature.

To accomplish this, he immediately ordered an extensive change of administrative personnel.

The selectors tried to turn things around with seven new faces in the team, the most extensive change of an England XI during a Test series since seven players were changed for the 1921 Ashes Tests against Australia at Lord's and Headingley (when only JWHT Douglas, Ciss Parkin, Lionel Tennyson and Frank Woolley were retained, and Tennyson replaced Douglas as captain).

In spite of the extensive loss of Clara, ciliated, and goblet cells, mice in which Sox2 was extensively deleted from the respiratory epithelium do not develop spontaneous infections and survive normally in the vivarium, indicating an unexpected compensatory capacity in the maintenance of homeostasis in spite of extensive changes to the structure of the conducting airway.

I've certainly made extensive changes to the structures of some of the books I've adapted, but never in a vacuum.