Sentence examples for extensive changes including from inspiring English sources

Ministers and other officials who were allotted bungalows also made extensive changes, including large additions and the construction of separate staff quarters on the plots.

A former Wall Street executive said last night that he thought the board should name an outsider with an outstanding reputation and give him a mandate to make extensive changes, including forcing changes in the board's membership.

In the prospectus, they described the properties as "ripe for repositioning," a task they said would involve extensive changes, including upgrading the menu at the restaurant, the Blue Whale, and revamping the hotel, called Le Ciel (though usually known by its former name, the Botel), to eliminate shared bathrooms and exposed cinderblock walls.

Sequence degradation may range from a single disabling mutation, such as a frameshift or an in-frame stop codon in a protein-coding gene, to extensive changes including numerous insertions and deletions [ 7, 16].

Thus, the speed at which this occurs has important implications for extensive faunal changes, including adaptive radiations and recovery from mass extinctions.

On the contrary, PCBs at the highest dose increased significantly lipid peroxidation in the kidneys and liver (4-fold) only in the bank voles raised under a long photoperiod; the PCB-induced hepatic lipid peroxidation was accompanied by extensive histopathological changes including hepatocyte enlargement, necrosis and steatosis.

Livers of 24-month old individuals showed extensive morphologic changes, including spongiosis hepatis, steatosis, ballooning degeneration, inflammation, and nuclear pyknosis.

However, both MCF-7/c3 and MCF-7/pv cells died after stimulation with TNF-α and CHX, either by apoptosis (MCF-7/c3 cells) or a different caspase-3 independent caspase-3 independentoduces extensive modehofogical changes includeathswelling and dethatment from the solid suproducesCF-7/pv cextensiveta not shown).

Other U12 introns were subject to extensive sequence changes including changes in the 5', 3', and branch site regions of the introns.

The development of colorectal cancer (CRC) is accompanied by extensive epigenetic changes, including frequent regional hypermethylation particularly of gene promoter regions.

Increasing IL-13 concentration caused extensive network changes, including a shift in MCP-1 and GM-CSF to a higher concentration and IFN-γ to a moderately high concentration (Additional file 5 panel A).