She made some extensive changes in the process.
The heavy betting favorite last year, Synchronised, died during the race, leading to extensive changes in the past 12 months to the Grand National course.
He led the charge for extensive changes in the listing requirements of the New York Stock Exchange -- changes that give far greater emphasis to the role of the independent director.
Along with passing the most extensive changes in the rules governing mutual funds since the 1940's, the agency has been investigating dozens of companies suspected of violating securities laws.
On the other hand, if material disadvantage is a major cause of ill health among the poor, then extensive changes in the environment in which the poor live -- for example, cleaner buildings and more parks -- are needed.
A striking aspect of America's educational system is the fact that extensive changes in the financing of higher education over the past three decades have failed to inspire a groundswell of discontent.
But advocates for subway riders said the lack of an announcement was yet another example of the transit agency's attempts in recent months to limit public input -- which usually becomes public outcry -- about the most extensive changes in the system in more than a decade.
At the operating level in industry and in public utilities, new techniques, new methods, new tools, new synthetics, new sources of power, and increased uses of automation have brought extensive changes in the past decades, and the rate of change tends to increase as time goes on.
More extensive changes in the organization of research are necessary.
Histological examination demonstrated extensive changes in the wall with high-grade fibrosis after application of ionizing radiation.
Exposure to UVR, in particular, induces extensive changes in the composition and architecture of the extracellular matrix (ECM -rich dECM -rich 8].
