Sentence examples for extensive changes in gene from inspiring English sources
More generally, chromosomal instability could provide a growth advantage to the cancer cell by causing extensive changes in gene expression via increased cell proliferation or decreased cell death.
The relevance of this prediction to dexfenfuramine-induced PAH is not clear, especially in light of the extensive changes in gene expression observed in these mice.
Differentiation of oligodendrocyte progenitor cells (OPCs) into mature oligodendrocytes requires extensive changes in gene expression, which are partly mediated by post-translational modifications of nucleosomal histones.
While we do not observe any consistent changes in plasma PSA levels over the 12 month period of the intervention, we were able to quantify extensive changes in gene expression.
Viral infection induced extensive changes in gene expression (Fig. 2, Additional file 3).
Divergent evolution of mammals also led to extensive changes in gene expression within and between lineages.
Our results show extensive changes in gene-level protein production between in vivo-derived slender BF (slBF) and insect midgut stages (procyclic cultured forms, PCF), greater in extent and magnitude than changes in mRNA abundance.
Despite extensive change in gene content and greatly increased rate of overall nucleotide substitution, C. obtusiflora also retains all photosynthetic and photorespiratory genes with only one minor exception.
Our study highlights the highly dynamic nature of the trebouxiophycean chloroplast genome, in particular with regards to the large IR sequence that experienced repeated losses and extensive changes in size, gene content, and gene order during evolution.
These studies have shown widespread disruption of transcriptional activity following iAs exposure with extensive changes in global gene expression, suggesting that diverse regulatory mechanisms of gene expression might be affected.
Microarray studies have revealed extensive changes in brain gene expression associated with honey bee behavioral maturation [ 11, 12] These studies used statistical models with discrete age classes to describe the changes in gene expression and cluster analysis to group genes according to their profile [ 11].
