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However, extensive bone loss due to disease or trauma requires tissue-engineering applications.
Restoration of extensive bone loss and defects remain as an unfulfilled challenge in modern medicine.
Revision of an acetabular component with extensive bone loss is a procedure that sometimes includes allografting or the placement of an unusually sized or positioned uncemented acetabular component.
In our recently published cross-sectional study we suggested that subjects with a complete SCI reach a new bone steady-state in the paralysed limbs after extensive bone loss was complete.
In this case, a jumbo cup was used due to extensive bone loss to ensure stable primary fixation.
Extensive bone loss necessitates a skeletal reconstruction with a tumour prosthesis, usually treated in a centre with specialist revision surgeons, specialist microbiologists and plastic surgeons.
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Huge and extensive bone losses occurred in the medullary cavity of the femur and tibia of a 55-year-old female rheumatoid arthritis patient with severe osteoporosis after debridement of her infected total knee arthroplasty.
Unlike biodegradable macromolecules, nonbiodegradable and biocompatible polymers such as polyhydroxyethyl methacrylate and poly styrene) could represent interesting solutions to generate permanent scaffolds supporting bone regeneration in case of extensive bone losses.
In femoral revision, the use of a fluted, tapered stem developed by Wagner [4, 5] allowed successful treatment even in cases complicated by extensive proximal bone loss, thanks to adequate distal fixation.
Management of extensive acetabular bone loss in hip revision arthroplasty can be a tremendous challenge.
The indication for revision surgery was painful aseptic loosening of the cup with extensive acetabular bone loss in 62 hips.
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