Although there may be more extensive barriers to shifting attitude or behavioural outcomes, changing knowledge around what people can do is an important outcome in itself.
Moreover, both the generally low levels of linkage disequilibrium across much of the A. gambiae genome which should minimize associations between focal synonymous SNPs and nearby adaptive variants, and the absence of extensive barriers to mosquito migration in this part of Africa which should erase the genetic signature distinguishing local M populations, render these alternatives unlikely.
The "Washington Post" described the organization as "carefully constructed with extensive legal barriers to shield its donors" and said it operated "de facto banks" that were "feeding money to groups downstream".
A 'through the gate' project, it provides practical and emotional support inside HMP Leeds and after release, helping men to overcome the extensive barriers ex-prisoners face and lead positive lives in the community.
The review also identified an extensive range of barriers to, and facilitators of, telehealth.
Health care providers in this study demonstrated awareness of an extensive array of barriers to PNC experienced by the inner-city women for whom they provided care.
Most studies including an extensive review of barriers to accessing HIV treatment and negative treatment outcomes suggest that longer distances from treatment sites are associated with poorer outcomes [ 37, 41].
However, despite extensive research on barriers to dental service-use [ 7, 12- 17] and oral hygiene-related behavior [ 18- 21] in which barriers have been associated with impaired mobility, impaired activities of daily living, low energy, depression, and lack of social support, it remains unclear how frailty in its many forms influences the oral care of older people.
Ostensibly, these diverse and extensive barriers hinder any form of advancement in this conflicted area.
Extensive barriers were reported, especially noticeable in Welsh units, where people were frustrated with the limited Trust or hospital management systems in place to effectively support their work and the ambitions of their units.
In many countries, however, where such structures are less developed or extensive, there are considerable barriers to developing evidence-based guidelines, as identified in the SEA-ORCHID project on the development of maternal and perinatal guideline development in hospitals in South East Asia [ 17].
