Sentence examples for extensive activation of from inspiring English sources
Electroporation of a construct encoding a Cre-enhanced green fluorescent protein (EGFP) fusion protein into explants from ROSA26 reporter animals resulted in extensive activation of β-galactosidase expression, indicating that the electroporated construct produced functionally active protein.
Here we demonstrate extensive activation of the hedgehog (Hh) pathway within the airway epithelium during repair of acute airway injury.
The most significant and life-threatening toxicity following CAR-T cell therapy is CRS, which is attributable to the rapid and extensive activation of infused CAR-T cells upon antigen engagement and results in elevated inflammatory cytokines (Lee et al., 2014).
These analyses show extensive activation of p53 downstream signaling by four lead compounds, and more limited by two.
Extensive activation of PARP-1 occurs after ischemia-reperfusion, trauma, and other conditions that cause DNA damage.
Okadaic acid and another protein phosphatase inhibitor, cantharidin, also induce apoptosis in lymphocytes and cause extensive activation of the JNK, ERK and p38 MAPK pathways [36], [37].
Graft-versus-host disease (GVHD) is driven by extensive activation and proliferation of alloreactive donor T cells causing significant morbidity and mortality following allogeneic hematopoietic cell transplantation (HCT).
Also at the 25 day time point, the injured bladder tissue appears to undergo extensive activation, infiltration, and migration of inflammatory cells ("immune response").
Perceiving scenes gave rise to extensive activation along the length of bilateral hippocampi, whereas scene construction was restricted to anterior hippocampus, and we identified a region of anterior medial hippocampus common to both.
Due to the extensive activation seen in this contrast, it was difficult to cluster the activations for the purposes of reporting useful Talairach coordinates for points of activation.
Patients had larger numbers of B cells (CD19+) and activated B cells (CD19+CD69+) than controls, consistent with the immune response classically reported for HAT, with the extensive polyclonal activation of cell likely to proliferate and to secrete large amounts of antibodies [14], [15].
