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Only FDC forms which accumulated excess electron dense deposit or exosomes demonstrated extensive accumulations of ubiquitin at the plasma membrane (Fig. 5A).
Because extensive accumulations of secondary oxyhydroxides of ferric iron are already present, remediation strategies for the ETMA should focus on mitigating the release of sulfide oxidation products rather than on preventing further oxidation.
Common to all NCLs, both neuronal and peripheral tissues from JNCL patients show extensive accumulations of lysosomal storage material, indicative of some form of lysosomal dysfunction.
Histologically, these perinephric cysts, which should be more accurately termed as 'pseudocysts', are locally extensive accumulations of fluid in fibrous sacs surrounding one or both the kidneys.
Histopathological studies in horses assessing samples obtained from glanderous lesions of the nasal septum have detected bacteria in the vicinity of extensive accumulations of disintegrating neutrophilic granulocytes and macrophages, indicative of intracellular invasion and survival [ 32].
Later, Lee and co-workers supported these seminal observations by identifying extensive accumulations of autophagic compartments in PSEN1-deficient cells, as well as in the brains of PSEN1 hypomorph or conditional knockout mice [ 69].
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Cd from dietary and smoking exposures can accumulate in various organs and tissues, but the most extensive accumulation occurs in the kidney cortex.
The sarcophagus, as well as mummies of a child, a falcon, a puppy and a cat, are part of an extensive accumulation of Egyptian treasures.
Durability, unsustainable use, and inappropriate waste management cause an extensive accumulation of plastics in natural habitats [[2]].
Rapid distribution and clearance from circulation of 68Ga-THP-mal-J591c-scFv was observed, with extensive accumulation in the kidneys, urinary bladder and liver, all reaching a plateau by 60 min.
It was initiated by sudden instability after the Deccan volcanism and resultant extensive accumulation of lava pile over continental lithosphere of northern India, northern-eastern tilt due to crustal thickness heterogeneity and subcrustal thermal stratification.
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