The phrase "extensive accumulation of" is correct and usable in written English.
You can use it to describe a large collection of something. For example, "The museum had an extensive accumulation of historical artifacts."
The sarcophagus, as well as mummies of a child, a falcon, a puppy and a cat, are part of an extensive accumulation of Egyptian treasures.
Durability, unsustainable use, and inappropriate waste management cause an extensive accumulation of plastics in natural habitats [[2]].
It was initiated by sudden instability after the Deccan volcanism and resultant extensive accumulation of lava pile over continental lithosphere of northern India, northern-eastern tilt due to crustal thickness heterogeneity and subcrustal thermal stratification.
Morphological examination of the liver by transmission electron microscopy (TEM) showed extensive accumulation of the second dose of mPEG2000-liposomes in the Kupffer cells, even already after 15 min, suggesting that the PEG liposomes had somehow lost the protective effect of the surface-grafted PEG against rapid clearance.
Furthermore, extensive accumulation of α-synuclein is associated with lysosomal alterations [22].
In addition, chemical inhibition of DNA-PKcs results into an extensive accumulation of DSB in human cells.
Only FDC forms which accumulated excess electron dense deposit or exosomes demonstrated extensive accumulations of ubiquitin at the plasma membrane (Fig. 5A).
Because extensive accumulations of secondary oxyhydroxides of ferric iron are already present, remediation strategies for the ETMA should focus on mitigating the release of sulfide oxidation products rather than on preventing further oxidation.
Common to all NCLs, both neuronal and peripheral tissues from JNCL patients show extensive accumulations of lysosomal storage material, indicative of some form of lysosomal dysfunction.
Histologically, these perinephric cysts, which should be more accurately termed as 'pseudocysts', are locally extensive accumulations of fluid in fibrous sacs surrounding one or both the kidneys.
Histopathological studies in horses assessing samples obtained from glanderous lesions of the nasal septum have detected bacteria in the vicinity of extensive accumulations of disintegrating neutrophilic granulocytes and macrophages, indicative of intracellular invasion and survival [ 32].
