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However, it is unknown whether untargeted or systemic delivery of ADC and/or free MMAE to neuronal bodies and their axonal extensions may occur.
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Inferolateral extension may occur through the cricothyroid membrane (or cricothyroid space where there is deficiency of membrane) to invade the soft tissues of the neck.
Therefore, the mechanical extension of CD4D1D2 may occur even at very low forces.
Most lesions arise in the metaphysis, but extension into the epiphysis may occur after epiphyseal plate closure.
We show that even at low forces mechanical extension of CD4 domains may occur at longer time scales.
Our findings show that mechanical extension of CD4 domains may occur within a broad range of forces.
Our results show that the mechanical extension of CD4 domains may occur within a broad range of forces.
Secondary tumour extension to the masticator space is also common and may occur by direct extension or by perineural tumoral spread.
Such devices suffer particularly when they reach force saturation of the actuators and maximum extension of their stroke, which may occur in case of severe loading conditions (e.g. wind gust and earthquake).
Inferior extension into the postcricoid area may occur submucosally and, therefore, is endoscopically undetectable.
Skin tears may occur during this extension.
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