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We also observed striking morphologic changes in cells, in which PERK signaling was selectively activated, including retraction of cellular extensions, loss of refractiveness under phase-contrast microscopy, and detachment from the underlying matrix (Video S2, Fig. 3A).
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The only limitation was 10° of extension loss.
This study showed that postoperative limitation in knee extension may increase the risk of extension loss.
The average knee extension loss was 12°, LLD 47 mm, PDFA 65°, MAD 2 mm.
Severity of extension loss was classified as shown in Table 1.
The hypothesis was that the hyperextension maneuver can decrease or eliminate knee extension loss after arthroscopic ACLR.
To our knowledge this is the first study to evaluate the effect of the hyperextension maneuver on knee extension loss.
It appears that ACLR may be performed with the knee in full extension during graft placement with excellent results and a very low rate of extension loss [16].
Note the extension loss at the involved right elbow (a) and dimple (arrow) at the posterior aspect of the elbow (b).
The knee ROM and extension loss were evaluated at each examination at 2, 6, 12 and 24 weeks and at 1 year postoperatively.
In their series of 57 patients who underwent patellar tendon autograft ACLR, only one patient had a mild (5°) extension loss [11].
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