Sentence examples for extension of trials from inspiring English sources

Unfortunately the impact of a new treatment in terms of HRQoL may not be fully captured in this timeframe so HRQoL should be considered with longer follow-up (e.g. in long-term extension of trials).

As long-term safety data for biologics are becoming available from large observational cohorts, such as those from national registries or from open label long-term extension of trials, it is reassuring to note that adverse effects tend to be more frequent in the early phase of treatment [ 23].

The peculiar system of development of early Roman law, by annual edict and by the extension of trial formulas, gave the Roman patrician legal expert an influential position.

Longer-term data are emerging [ 39- 44], but these are even less comparative as most are open-label extensions of trials where most patients were switched to active treatment regardless of original assignment.

Data from the open-label extension of pivotal trials and a successive randomized, placebo-controlled long-term study showed that benefits were sustained with prolonged treatment up to 12 14 months [25, 26].

A total of 327 patients were enrolled in a 1-year, open-label safety extension of four trials.

Open label extension of exenatide trials showed that the glycaemic control in the long term was similar to the effect shown in the Heine trial.

In a 9-week extension of these trials, asenapine met criteria for noninferiority to olanzapine in the treatment of mania [ 16].

These findings encourage an extension of clinical trials of mTOR inhibitors from patients presenting genetic forms of autism to populations of schizophrenic patients and reciprocally suggest that 5-HT6 antagonists might be evaluated in autism.

Two phase III trials have been published in peer-reviewed journals and one has recently become available in abstract form only. Three ancillary studies and an open-label extension of these trials are available in abstract form only. Two phase III studies from Japan are also available only in abstract form.

In order to judge the contribution of the extension of field trials to the accuracy of prediction of genomic selection, cross-validation across genotype was performed separately within population A and population B for grain yield and plant height based on increasing numbers of environments, that is, location-year combinations (CVG Env; Figure  3).