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Occult microscopic extension of a tumor that was not detected on endoscopy was found in a further 50% of patients.
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Whether this tumor type is an extension of a retroperitoneal tumor of true visceral origin, derived from ectopic paraganglia, remains unknown [ 1, 2].
Lateral and longitudinal extension of a skin tumor could be defined by clinical observation within a safety margin, but depth and the possibility of involvement of deeper structures may remain unknown.
Optic disc involvement is due either to direct extension of a choroidal tumor which is located close to the optic disc or to hematogenous spread of neoplastic cells to the circulation of the papilla [ 28].
Tumor related PET/CT findings include the perineural spread of HN tumors which represents a rare contiguous metastatic extension of tumor along a cranial nerve that portends to poor prognosis, even if the patient is asymptomatic [ 2, 5].
* P < 0.05 Likewise, the TGFBI methylation status of prostate cancer specimens was correlated with pathological features of the patients' prostatectomy specimens including those of locoregional invasiveness (i.e., extracapsular extension of tumor, seminal vesicle involvement by tumor, margin positivity with tumor, and/or regional lymph node tumor involvement) (Table 4).
This contrast is not visible in the white light images of the lesion and likely represents an extension of the tumor margin and associated inflammation that is present below the normal-appearing surface epithelium of the area.
The ciliary body may be affected either directly or by an extension of a choroidal or iris tumor.
Perineural invasion is evident on CT when there is direct extension of tumor involving a known perineural pathway.
The patient was diagnosed elsewhere as having an extraocular extension of intraocular tumor and advised radiation brachytherapy for the same.
Thus, the extramural extension of the tumor on HR MRI is a key factor in determining prognosis, therefore allowing proper selection of patients for preoperative treatment.
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