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Then, fourth RPLKPW was also introduced into the extension domain of the protein.
The minimum effective dose of the modified extension domain was 1.0 mg/kg, which is 1/2000 that of ovalbumin.
Furthermore, we produced an extension domain that corresponds to residues 1 143 of the modified α′ subunit containing four RPLKPW sequences by introducing a termination codon.
Trimmed geometries, as common in CAD models are efficiently handled by an embedded domain method which treats trimmed areas as a fictitious extension domain in the computational model.
As described above, the TERT protein has a conserved structural organization that is divided into four functional domains; the N-terminal extension domain, the TR-binding domain, the catalytic RT domain, and the C-terminal extension domain (Figure 6A) [6].
Since the N-terminal extension domain (NTE) is a conserved structural feature of HMT-1 proteins, unique to this half-transporter family, we expected that it may be critical for HMT-1 function.
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We prove a high order Poincaré inequality for f minus a polynomial of order m−1 over the entire space G or unbounded extension domains.
In this paper, we investigate the validity of sharp global Poincaré inequalities of both first order and higher order on the entire nilpotent stratified Lie groups or on unbounded extension domains in such groups.
In support of this, recent work showed that in prokaryotes the extension domains of some r-proteins, including the rpL17 homologue L22, are not required for in vivo assembly of ribosomal subunits [57], [58].
The TBDTs in other operons beyond the Methylosinus (Group I) species lack N-terminal extension domains and are not adjacent to FecIR homologues.
As a corollary we prove that the property of being a W1,p-extension domain, 1
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