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While alternans in a single cardiac cell appears through a simple period-doubling bifurcation, in extended tissue the exact nature of the bifurcation is unclear.
A mouse-adapted H9N2 virus, generated by serial lung-to-lung passage, gained improved growth characteristics in mammalian cells, extended tissue tropism in mice, and was lethal for mice (Wu et al., 2009).
The greater hospital resource use, costs, and complication rates associated with oncologic surgical resections relative to benign indications could be attributed to several differences in the surgical techniques required, extended tissue resection for adequate margins, lymph node dissection for staging, and/or the resection of ancillary tissues [13 15].
We first performed e-Northern analysis with the Expression Browser at BAR using the AtGenExpress extended tissue and stress series data sets for the AtHsp90 gene family.
The expression profiles of Hsp90 and CC-TPR genes were examined against the AtGenExpress extended tissue and abiotic stress data sets using the Expression Browser tool available at the Botany Array Resource (BAR) (http://bbc.botany.utoronto.ca/affydb/cgi-bin/affy_db_exprss_browser_in.cgi) [31].
Software custom written in LabView (National Instruments, www.ni.com) allowed the user to digitally resample extended tissue volumes on arbitrary planes.
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In this chapter we will review emerging approaches to engineer tissue interfaces using monolithic scaffolds, scaffolds assembled from separate tissue layers, and approaches to extend tissue engineering techniques to current clinical techniques for the purpose of repairing or regenerating tissue interfaces.
As a consequence, depending on the cancer stage, i.e. to which extend tissue has to be re-organised upon cancer invasion, senescence could be pro or anti tumorigenic.
Moreover, this method uses small amounts of biopsy tissues and can be easily extended to tissue samples submitted for conventional histopathological evaluation.
The future goal of the described technique is to perform even extended soft tissue interventions utilizing a minimally invasive endoscopic approach.
Motility contrast imaging recently has been extended to tissue dynamics spectroscopy (TDS) [ 44] that is a coherence-gated form of diffusing wave spectroscopy [ 45, 46].
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