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With extended treatment, the median response duration for the 3 mg/kg dose had not been reached at the time of analysis (range 16.1+ weeks to 133.9+ weeks).
Impressively, the therapeutic response duration with nivolumab has been extended beyond 2 years [ 23].
Most series report response rates of 60%to7070% with a median response duration of approximately 10 months.
Response duration was defined as the interval from anemia response to loss of response, change of therapy, or death.
The results confirmed the superiority of VRD in increasing PFS, response duration, and OS34.
Response duration was calculated using the Kaplan Meier method and compared by the log-rank test.
Response duration was longer in the thalidomide/prednisone/danazol cohort (HR 2.18 (1.18–5.42); P = 0.019).
Responses to treatment were evaluated by response rates and response duration.
The median response duration was 59 weeks.
Median response duration was 51 weeks.
Median response duration was 19 months (4 42).
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