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The simulated polyglutamine loop insert predominantly adopts extended random coil conformations, a structural model consistent with low resolution experimental methods.
We solve the problem with a newly developed extended random search algorithm and tested it in a realistic design optimization problem based on the Horns Rev 1 offshore wind farm in Denmark.
The two leading RP-HPLC approaches for deriving hydrophobicity values of amino acids utilize either sets of designed synthetic peptides or extended random datasets often extracted from proteomics experiments.
The IDP Osteopontin (OPN), a cytokine involved in metastasis of several types of cancer, is shown to simultaneously sample extended, random coil-like conformations and stable, cooperatively folded conformations.
In this article, the terms "intrinsically disordered proteins" and "intrinsically disordered regions" (IDPs and IDRs, respectively) are used to describe such proteins and regions generally and "natively denatured" or "intrinsically unstructured" are used for collapsed and extended random coils that lack significant amounts of stable secondary structure (see below).
The experimental data were adequately reflected by the extended random sequential adsorption model (eRSA).
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By analogy, the threshold model may be extended by random terms.
The developed approach can be extended to random regressions, covariance functions, spline, gametic and variance component models.
The basic stochastic characteristics of the homogenized elasticity tensor and its deterministic sensitivity coefficients are verified with such coming from analytical deterministic homogenization method extended towards random case in the computer algebra system MAPLE®.
From the copolymer composition dependence of miscibility the segmental χ parameters of HMA/MMA, EHMA/MMA, EO/HMA and EO/EHMA were estimated using the Flory–Huggins theory extended to random copolymer systems.
The theory of probabilistic normed spaces was initiated and developed in [14, 15] and further it was extended to random 2-normed spaces by Goleţ [16] using the concept of 2-norm of Gahler [17].
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