Sentence examples for extended linkage from inspiring English sources

The use of related individuals also do not provide much extended Linkage Disequilibrium information compared to unrelated individuals of same population.

A recent study confirmed that the ADAM33 locus shows extended linkage disequilibrium upstream of ADAM33 to GFRA4, as well as downstream including SIGLEC1 (also named sialoadhesin SN) [38].

Isolated populations are a useful resource for mapping complex traits due to shared stable environment, reduced genetic complexity and extended Linkage Disequilibrium (LD) compared to the general population.

Data from HapMap also demonstrated extended linkage disequilibrium in the region in East Asian and European population, and significantly low degree of genetic differentiation among human populations.

Including this one, ten studies have scanned the human genome for regions of selective sweeps to date, with varying levels of success by utilizing extended linkage disequilibrium, elevated divergence and reduced homozygosity [4], [9], [17] [23].

Several previous analyses of selective signatures have appeared which have been based either on decreased heterozygosity (H), population differentiation (FST), extended linkage disequilibrium, and even the premise that certain modern hereditary disease alleles were adaptive sometime in the past [3], [4], [6] [15].

With a view to marker-assisted breeding and map-based gene cloning, there is interest in extending linkage maps to include molecular markers.

The five sites highlighted in this report fared better, with all five extending linkage activities in some capacity for at least several months beyond the end of project funding.

To improve the resolution of QTL mapping for HD and OA in dogs, we extended our linkage population (Greyhound, Labrador retriever and their crosses) to include six additional breeds to reduce the extent of linkage disequilibrium (LD) between the mutation and SNPs in a genome-wide association study (GWAS).

However, we were unable to narrow down the region and instead extended the linkage to the other side of the centromere.

The protein encoded by the CDH13 gene is one of numerous cadherins expressed in the brain, which have been shown to regulate many neural processes (Redies et al. 2012) and CDH13 has been implicated in ADHD through genome-wide association and extended pedigree linkage studies (Lesch et al. 2008; Rivero et al. 2012).