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The analysis presented is logical and supports the revised and extended hypothesis.
6 To test this extended hypothesis we performed time-dependent UV vis spectroscopy experiments in which apo-FbpABp was added to ferric siderophore complexes, and the characteristic CT band for the ferric siderophore was monitored over time.
To test the extended hypothesis, we made a triple mutation (R64A/K71A/R74A, human α1 numbering, 'AAA mutant'), in the context of the recombinant human α1β2γ1 complex used in Figure 3, of the three basic residues in the kinase domain that we propose to interact with phosphate groups on the ST loop.
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Regardless, there is virtually no support for a life span extending hypothesis for A-bomb survivors and other exposed subjects.
However, there is virtually no support for a life span extending hypothesis for A-bomb survivors and other exposed groups [ 16].
Use of PD biomarkers in early clinical trials extends hypothesis testing and confirms whether a drug hits a tumour target (proof of mechanism, POM) and thereafter, the anticipated tumour outcome is reached (proof of concept, POC).
This finding, along with the further increases in cortical ACh efflux associated with task performance, extends hypotheses regarding the crucial role of cortical cholinergic transmission for attentional functions.
This work complements and extends hypotheses presented in our previous studies [3], [9], [10], [20], [53].
Recently, William Parker extended this hypothesis to the " Lost Friends Theory" or the " Biome Depletion Theory".
It explored the hypothesis that low milk protein content is associated with lower fertility and extended this hypothesis to also evaluate the association of CN contents with fertility.
Also currently debated is whether the cargo-loaded receptor remains associated with the pore (shuttle hypothesis) or whether it is released as a soluble receptor-cargo complex into the peroxisomal matrix (extended shuttle hypothesis).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com