The cytoplasmic filaments, composed mainly of Nup358, extend flexibly into the cytoplasm and contain four RanBP1-like domains [ 27].
At the same time, we expect that the ontology provides a conceptual foundation that can incorporate a range of additional dimensions and concepts in vulnerability, which currently are not considered, and that the ontology can be extended rather flexibly in a way that will not require a total revision of the existing structure.
In this context, it is intriguing that LACV and influenza contain, respectively, an α- or β-ribbon, equivalently located extended and flexibly hinged structures that could both play a role in both RNA and NP interactions and could be adapted to the respective NP structures (Reich et al., 2014).
The functions provided by the Social BIMCloud framework can be flexibly extended by integrating external applications like cost analysis and energy simulation software through APIs provided by the respective software.
Upon the availability of suitable PK/pharmacodynamic (PD) models for adalimumab's efficacy end point in specific disease populations, the current mechanistic model may be flexibly extended for predicting loss of efficacy due to ADA development.
From a scientific perspective, the TDM database can be regarded as a basic tool for the implementation of multi-centre clinical trials and observational studies since the body of data collection can be extended or changed flexibly, depending on the aims of the respective study.
Patients were enrolled in an 8-week, prospective antidepressant monotherapy phase (Phase B), and received 1 of 5 antidepressants (fluoxetine, paroxetine [either immediate- or controlled-release [CR] formulation], sertraline escitalopram, or venlafaxine extended release [ER]), flexibly dosed, along with co-administration of a single-blind placebo.
Practically, the IP modules can be flexibly reused, extended, and migrated to other independent platforms very easily.
To overcome this problem, this study proposes a novel Viterbi-based [9 11] algorithm, called the jiggle-Viterbi with substate selection (JVSS) algorithm, which flexibly uses extended substates for joint symbol period compensation, data sequence estimation, and signal frame synchronization.
Furthermore, it serves as a means for flexibly extending a MESHMdl daemon.
