Sentence examples for extended efficacy from inspiring English sources

Recent studies 26 indicate that it has extended efficacy in controlling delayed CINV compared to the first-generation 5-HT3 receptor antagonists.

The plasma elimination half-lives of palonosetron (>40 hours) and netupitant (~96 hours) are long, likely contributing to the extended efficacy during the delayed phase (25 120 hours) following chemotherapy administration [ 10].

In addition, a potential for an extended efficacy time window might occur if the importance of activated glia is key early in progression and neuronal stress is more critical at later time windows of progression, allowing for the same drug to have extended pharmacodynamics via action in overlapping but distinct pathology progression time windows.

To effectively build on the recent successes of immune checkpoint blockade, adoptive T cell therapy and cancer vaccines, it is critical to rationally design combination strategies that will increase and extend efficacy to a larger proportion of patients.

However, it is increasingly recognized that observational studies can complement RCTs by supporting and extending efficacy findings from RCTs to real-world clinical practice, particularly across geographical populations.

Several new approaches are being studied not only to improve treatment efficacy related to pain response but also to extend efficacy by improving overall survival.

Hence, EGCG extended the efficacy of cysteamine in vivo, significantly reducing the mRNA expression of Tnf (P < 0.001) and Cxcl2 (P < 0.01, the Student t test) (Fig. 3 D).

To test the validity of our hypothesis, we are currently evaluating how genetic manipulations that alter the abundance of various extra-nuclear target proteins of Rim15p or affect their phosphorylation status influence the life-extending efficacy of LCA.

Altogether, the results of our pharmacophore modeling of the anti-aging potential of bile acids imply that the maintenance of the minimal polarity of both the hydrophilic (concave) and hydrophobic (convex) sides of the steroid nucleus - by avoiding the presence of polar substituents at the positions 6, 7 and 12 - is mandatory for the extreme life-extending efficacy of LCA under CR conditions.

Due to downy brome's relatively short seed viability in the soil, extending herbicide efficacy to several years could help to reduce the soil seed bank.

In the future, new approaches, such as three‐dimensional (3‐D) drug distribution modeling and the use of multiple drug‐releasing implants, will be used to extend the efficacy of these implants in treating larger tumors more similar to intractable human tumors.