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Patients who responded to treatment with stable disease (SD) or better could receive extended dosing.
Of these, dalbavancin and oritavancin offer extended dosing intervals.
This extended dosing offers potential advantages for patient convenience and clinic efficiency.
Thus, extended dosing may simplify anemia management for patients, care givers, and health care providers.
Moreover, 70% of patients were receiving darbepoetin alfa Q2W at month 12, indicating that most PD patients were successfully maintained on extended dosing frequency.
To evaluate extended dosing intervals (EDIs) with lanreotide Autogel 120 mg in patients with acromegaly previously biochemically controlled with octreotide LAR 10 or 20 mg.
As measured in PBMCs, extended dosing with lomeguatrib successfully depleted MGMT for the duration of treatment, and resulted in the persistence of DNA damage.
While benefiting patients, both self-/partner or HCP injections together with extended dosing intervals (EDIs) also have the potential to reduce the economic burden of the disease.
This study provides evidence for the utility and efficacy of darbepoetin alfa extended dosing, and for the ability to synchronize dosing with chemotherapy administration.
A subsequent amendment added an extended dosing schedule (EDS) of 500 μg every three weeks (Q3W) to the prescribing information in 2006.
This adverse event profile has been observed for rituximab when used in a variety of settings, including extended dosing, retreatment, and in combination with various chemotherapy regimens.
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