While resistance emergence is more likely within such a strategy, the implications for epidemic control are strongly dependent on the relative fitness of mutant strains, with the potential for either reduced or extended delays to an uncontrolled outbreak.
Though plants may revert to contingency plans, extended delay in manufacturing could leave companies scrabbling to find the parts they need as quickly as they can manage.
There are three distinct responses to chromosome tip damage: 1) lack of furrow initiation, 2) an extended delay in furrow initiation, but eventual cytokinesis, or 3) furrow initiation followed by furrow regression.
Whether the lag time is due to delay in diagnosis or due to delay in treatment initiation, population-based studies reveal extended delays in access to cure in many LMIS.
Failure to recruit sufficient numbers of participants, or extended delays in recruitment can have serious implications for the success or otherwise of the trial.
Occasionally, there were extended delays in communication when family members could not be reached because they lacked funds to purchase phone cards.
The new printers, The Carlton Press, failed to keep to the agreed printing schedule, and produced poor quality work; there were also printers' strikes, and this disruption caused extended delays in the appearance of the seventh issue.
Arrangements can be made "regarding fellowship resources should such students face extended delays or barriers to entry," Knuth wrote.
Additional challenges arose during the rainy season when treacherous road conditions led to extended delays.
