Sentence examples for extended circulation from inspiring English sources

A massively extended circulation will give NME an enhanced platform to break new bands, giving the title fresh credibility among readers and advertisers alike.

3,4-Difluorobenzylidene curcumin (CDF) is a nontoxic analog of curcumin (CMN) developed in our laboratory, which exhibits extended circulation half-life, while maintaining high anticancer activity and improved pancreas specific accumulation in vivo, compared with CMN.

Compared to traditional drug delivery systems, nano-based drug delivery system have greater potential in a variety of areas, such as multiple targeting functionalization, in vivo imaging, combined drug delivery, extended circulation time, and systemic control release.

In this study we wanted to determine whether highly charged cationic liposomes with surface-associated PEG could be designed to exhibit extended circulation lifetimes, while retaining tumor vascular targeting properties in an HT29 colorectal cancer xenograft model.

We show for the first time that it is achievable to design highly charged, highly pegylated (20 mol% DSPE-PEG2000) cationic liposomes which exhibit both extended circulation lifetimes and tumor vascular targeting properties.

While particles resembling red blood cells (RBCs) in size, shape and deformability have extended circulation times and altered biodistribution profiles compared to rigid, but otherwise similar particles, the in vivo behavior of such highly deformable particles of varied size has not been explored.

CTAB surface molecules were then exchanged for 5000 dalton polyethylene glycol (PEG) chains to improve biocompatibility, stability in salt solutions and serum, and extend circulation times [ 27, 31].

The micellar self-assembly increases the size of the targeted delivery system, extending circulation and exposure to the tumor by reducing glomerular filtration.

Further, PSA has properties similar to polyethylene glycol (PEG), a polymer commonly used to extend circulation time via incorporation into nanocarrier systems or protein conjugates [ 25, 39– 41].

Liposomal encapsulation of SOD has been found to increase its performance, extend circulation, and reduced membrane peroxidation in different areas of brain [ 78, 79].

Nanocarriers can be designed to avoid extravasation to normal tissues and recognition by cells of the reticuloendothelial system (RES), thereby extending circulation time in blood.