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Due to the short biological half-life, extended administration is required for more robust cartilage healing.
No difference was observed between intermittent and extended administration of meropenem and between beta-lactam mono- or combined therapy.
Indeed, multi-component botanical therapeutics such as phenolics may become particularly valuable in the long-term prevention and treatment of complex diseases requiring extended administration and pleiotropic action [ 13].
These findings raise the possibility that extended administration of galactose to lower Palb in patients with resistant FSGS may reduce proteinuria and delay progressive decline in kidney function [ 27].
Removal of iron from the brain may require repeated or extended administration of a chelator since very short-term chelation therapy (less than 3 h) to young rats (15 days) did not appreciably reduce radiolabel iron in the brain that was administered 2 or 24 h prior to chelation (Crowe and Morgan, 1994).
C.E.R.A. (methoxy polyethylene glycol-epoetin beta), a continuous erythropoietin receptor activator, was developed to provide stable control of hemoglobin (Hb) levels at extended administration intervals in patients with chronic kidney disease.
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For all study parts, patients demonstrating at least stable disease (SD) could receive extended administrations of siltuximab at the assigned dose (q3w for ⩽4 total infusions (part 1), or q3w (part 2) or q2w (part 3) for up to ⩽6 infusions).
That is now the central point of the new White House outlook on engagement, and it extends, administration officials say, to Venezuela, North Korea and Cuba as well.
Furthermore, extending administration time can improve the PK/PD indices of the two drugs, and further improve clinical efficacy.
Although the study is a pilot research, the trend illustrate the higher concentration might be got with extending administration, so when it is not effective of cefoperazone/sulbactam in bacterial meningitis, the administration method might be another choice.
I don't see anything socialist in this provision, but the administration did extend government power to insist that the insurance companies sell such policies at fair prices.
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