Your English writing platform
Discover LudwigExact(14)
We show here that a third functional domain of the Egr-1 protein, localized between the extended activation domain and the zinc finger DNA binding region, acts as a transcriptional repressor domain when fused to a heterologous DNA binding domain (DBD).
While they focused on temporally extended activation that persisted throughout entire task blocks, the present findings point to a direct analog at much shorter intervals.
Likewise, NF-κ B is a potent inhibitor of apoptosis, whose extended activation can promote cancer.
The resulting extended activation of Gαs leads to increased activity of adenylate cyclase, raising intracellular cAMP levels.
In contrast, more pessimistic (non-hardy) threat appraisals would lead to more rapid relinquishing of executive control, and reversion to more basic fear-based responses, and the extended activation states associated with sympathetic nervous system dominance.
Several mechanisms could account for the extended activation in the contralateral hemisphere in this study.
Similar(46)
This result is apparently at odds with the results of Diaz and McCarthy (2007) study, who did report extended activations in the left inferior frontal gyrus during a subliminal semantic task.
A second question concerns how best to extend activation approaches to benefit recipients of working age who are not as close to the labour market as the typical recipient of UI benefits.
Recently, Wang et al. revealed that GL331, a topoisomerase II inhibitor, activates autophosphorylation of ATM at S1981 and extends activations of DNA damage signaling pathways including TP53/p21 and Chk2/Cdc25A cascades to reach S phase arrest in HepG2 cells (Table 1) [ 146].
Overall, these results indicated that both the peak level of the HPA axis activity and time window of the activation were directly related to the intensity of stress, and that although the transgene did not increase the peak level, it significantly extended the activation time of both ACTH and CORT.
Activating a hospital-wide trauma response for every elderly patient injured in a low fall would be disruptive and impractical, but a tiered trauma response may allow early senior clinician assessment with rapid access to advanced diagnostics for elderly fallers 20 and some institutions have extended their activation criteria to include elderly patients with head or torso injury from low falls.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com