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In all three mutants, developing tracheal tubes bud and extend normally, but the epithelial walls of the tubes do not expand uniformly, and the resultant tubes are grossly misshapen, with constricted and distended regions all along their lengths.
This observation indicated that some of the mutant motor neuron axons failed to reach or extend normally along the dorsal nerve cord.
Fast muscle fibers were multinucleated (Fig. 5E; supplementary material Fig. S4) and extended between somite boundaries in mutants, suggesting that muscle cells fuse and extend normally (Fig. 5E).
The arrows indicate where Baz is preserved at the LE of those cells that do not elongate properly, while the asterisks mark the DME cells that extend normally, and have a reduction of Baz signal in the junctions.
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The relation between the layer thickness of the LC phase and the molecular weight suggested that the main chain was extended normally to the interface of the microphase separation.
Two daughter nuclei that were asymmetrical in size or lagging chromosomes were often observed in the dis3-54 Δmutantouble mutant cells, suggesting that although the spindle was extending normally, chromosome segregation was unequal.
In contrast, our analysis of the Dicerfl/fl; cre+ mutant mice showed that, although the axons extended normally toward the midline, a number of severe abnormalities were apparent at the optic chiasm (Figure 7B).
In morphants, secondary sprouts extended normally to the HMS (Fig. 1E) but then failed to turn laterally or anteroposteriorly (Fig. 1E′).
Over the course of the imaging period, peripheral sensory axons extended normally in aSyn-expressing neurons (supplementary material Fig. S2B), and cell survival between the first and last time point was not different between the two groups (supplementary material Fig. S2C).
More dramatically, "deep water" rice varieties can extend their normally centimeters-long stems up to 4 meters or more as water rises, keeping the tip of the stem, rice flowers, and topmost leaves above water (see video).
In Figure 5, the eya, six3, and dach1 morphants look as if they did not extend arms normally.
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