"The goal of my lab in the past 10 to 12 years has been to go inside these little columns and try to figure out how they are built with exquisite detail," said Henry Markram, a research scientist who is head of the Blue Brain project.
However, these drugs are engineered with exquisite precision, the products of decades of research.
(Telescopes and cameras are a different matter, as optics don't allow the same sort of miniaturisation).Each sprite's sensitivity would be quite low compared to a single exquisite measuring gizmo launched on a large-scale research satellite.
Exquisite imaging is also a feature of the research by Mai Nguyen-Chi, Georges Lutfalla and colleagues, who were able to model chronic inflammation using a transient Escherichia coli infection model in the notochord.
The ability to use organoids for discovery research, and the need to both exert exquisite experimental control and obtain quantitative measurements from organoid models means that the field is ripe for collaborative efforts between biologists, engineers, clinicians and industry.
Key to the success of these studies have been the insights into DNA repair pathways made in basic academic research, as well as the availability of exquisite PARP inhibitor probe compounds pioneered in industry.
The required expertise to 'solve' each case included molecular and computational biologists, geneticists, pathologists and physicians with exquisite knowledge of the disease and of treatment modalities, research nurses, genetic counselors, and IT and systems support specialists, among others.
Intense efforts aimed at understanding and exploiting their exquisite molecular specificity have positioned antibodies as a cornerstone supporting basic research, diagnostics and therapeutic applications [1].
Also the research part continues and this gives the research team an exquisite opportunity of monitoring the maintenance of effects in the long term.
Searching for a strategy to enhance the efficiency of nucleic acid amplification and achieve exquisite discrimination of nucleic acids at the single-base level for biological detection has become an exciting research direction in recent years.
