Adipocyte differentiation is tightly controlled by a transcriptional cascade, which directs the extensive reprogramming of gene expression required to convert fibroblast-like precursor cells into mature lipid-laden adipocytes.
Moreover, there appears to be a threshold of WT α-syn expression required to induce PD-like pathology.
The inhibition of α2-integrin expression (Iint,av) at steady state was chosen as the measure of inhibition of α2-integrin expression required to achieve these goals.
Indeed they seem to be essential to trigger gene expression required to prepare an adequate damage reaction in the surrounding tissues and organs.
It is possible that NR mice did not achieve the threshold of FIX expression required to halt the immune response, due to variability in transduction efficiency.
Nodule-specific expression of transcription factors highlights the changes in gene expression required to accommodate nodulation and symbiosis.> -wrap-foot> Transcripts must have an RPKM ≥1 to be considered expressed.
We detect a well-defined threshold level of exogenous GATA factor expression required to flip this switch and induce differentiation, and find that MAPK signaling sets this threshold dose.
The method of choice and the level of HER-2/neu protein expression required to obtain a potential therapeutic effect from trastuzumab monoclonal antibody therapy has not yet been established in lung cancer.
These results confirm that c-Myb expression is required to maintain expression of the CCNB1, CXCR4, JUN and KLF4 genes in MCF-7 cells, suggesting that these genes are endogenous targets of c-Myb.
These results strongly suggest that REST expression is required to repress non-neural expression of NRSE-containing transgenes.
