Three out of five recurrences displayed high synaptophysin expression, one of which also displayed high and one low β-catenin nuclear staining.
Multiple modes of regulation are most likely responsible for controlling SEPT9 isoform expression, one of which, as we have shown, is epigenetic silencing via DNA methylation.
He had remarkable expressions, every one of which I think I could still imitate perfectly today, nearly 20 years later.
This may be explained by the multiplicity of molecular mechanisms regulating gene expression, only one of which is DNA methylation.
Our previous studies defined an Alopecia Areata Disease Activity Index ALADINN) biomarker for response to treatment (Xing et al., 2014), which monitors three distinct gene expression signatures, one of which is the IFN response.
We envisage two possible mechanisms of how Utx could function to activate the expression of HOX genes, one of which depends on the H3-K27me3 demethylactivityvity of Utx and another that acts independently of this enzymatic activity.
This interesting finding provides detailed analysis of individual components of the TGF-β pathway and parallels recent reports on the existence of two distinct gene expression profiles in SFBs, one of which is characterized by the expression of TGF-β/activin A-inducible genes [ 7].
As of July 2014, there were 41 experiments and 453 comparisons available for mbtB gene expression data in PATRIC, one of which includes iron-dependent gene expression (Rodriguez et al., 2002).
Interestingly, Yam-1 displays a cis effect on the expression of neighboring genes, one of which encodes miR-715, which targets and represses Wnt7b in skeletal muscle [ 150].
P53 acts as a transcription factor that induces the expression of many genes, one of which is mdm2, that codes for a protein Mdm2 that shepherds translocation of P53 from the nucleus to the UPS for degradation.
