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The regular expressions of docking motifs Da and Db were kept inclusive to account for MAPK induced phosphorylation in multiple eukaryotic species.
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Furthermore, there is increasing evidence that Gab2 expression levels or the abundance of cells with prominent expression of the docking protein increase during CML progression from chronic phase to blast crisis [ 25, 26].
To explain MAPK docking with HIV proteins in a strain independent manner, we impose slight revisions on the regular expressions of previously annotated docking motifs.
We revise the regular expressions of previously annotated MAPK docking patterns in order to provide a subtype independent motif that annotates all HIV proteins.
Furthermore, the expression level and functional activity of docking factors and exportomer proteins have to be adjusted [ 56].
The number of docking sites affects the drug docking speed.
Thus, please beware of docking!
1. Method and assessment of docking accuracy.
Curated protein structures, docking grids, complete list of Docking Scores, and docking poses for all compounds are available upon request.
Figure 3 Illustration of docking settings.
This partial loss of docking is consistent with the idea of multiple docking pathways in synapses.
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