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Decreased numbers of PCNA and VEGF expressions in group V were seen as compared with their counterparts.
MyD88 and NF-κB p65 expressions in group B had significant differences compared with that in group A at 12 weeks (p < 0.05).
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Mucin phenotypic expressions in groups A, B, C. Table S4.
UHRF2 showed a high expression in group "a" and low expression in group "b".
Results showed a significantly higher level of VEGF protein expression in group 1 compared to group 2 (P≤0.001) throughout the investigational period.
According to our results, a significant increase of caspase-3 and Bax proteins expression in group II were detected (Figs. 5 and 6).
The expression of the marker is reduced in case of group C, mice treated with genistein, compared to group B, but higher than the expression in group F. This allows us to assert that genistein possesses anti-inflammatory proprieties, but milder than the ones of indomethacin.
Specifically, IL6 had a higher expression in group 1 than in group 2 (p-value = 0.021) and IL1B, although expressed at low levels, remained stable, decreasing slightly after the 4th 7th day post-fracture (p-value = 0.087).
AM HLA-DR expression in group A was lower than in group B (P < 0.05).
PBM HLA-DR expression in group B was lower than in group A (P = 0.01).
MSX1 and ZIC2 both displayed significantly higher gene expression in group 3 tumours.
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