Sentence examples for expression variants from inspiring English sources

9, 25– 32 Studies of schizophrenia in twins 33, 34 support reduced penetrance (genetic variants that do not express in every carrier as disease) and variable expression (variants that express as different diseases in different carriers), 35, 36 which is common to most human genetic diseases.

A main prerequisite for a successful epMEGAWHOP experiments is a reliable high-throughput screening system which allows an identification of improved expression variants.

Current strategies focus on the transcriptional events that specify vascularization and fiber formation and how the composition of lignin is modified in expression variants in the natural population.

We discuss the evolutionary implications of these findings for the origin and maintenance of expression variants in human populations, as well as for further genetic epidemiologic and pharmacogenetic studies.

Quantitative protein abundances (iBAQ-scaled, see 'Materials and methods') from expression variants and isoforms that originate from the same gene were aggregated by summation.

As light is a crucial environmental factor affecting plant growth [ 31], we evaluated the growth dynamics of the various AtCHR23 expression variants under different light regimes.

We found that genotypes that were characterised by a higher 5-HT transmission demonstrated a higher 'loss rate' of internal duration representation: 5-HTTLPR SS versus LL polymorphism, 'low expression' variant (3) versus 'high expression' variant (4) of MAOA VNTR gene, and T versus CC polymorphism of 5-HT2a T102C gene.

Furthermore, outside of high expression variant #1, the stationary variants #1 and #3 demonstrate the highest Vmax values.

The variable number of tandem repeat (VNTR) polymorphism of the MAOA gene present in 2, 3, 3.5, 4, or 5 copies [18]: variants with 3.5 or 4 copies of the repeat sequence are transcribed more efficiently ('high-expression variants') than those with 3 or 5 copies of the repeat ('low-expression variants').

Therefore, higher 5-HT transmission is related to the T allele of 5-HT2a gene, the S allele of the 5-HTT gene and 'low-expression variants' of the MAOA gene.

For this reason, low-expression variants, which are the most difficult to detect, sometimes showed differences among these studies.