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Establishing standards is particularly important for gene expression technologies due to the inherent technologic and biological "noise" in these systems.
In these cases, high-throughput expression technologies can provide verification that annotated genes are expressed, thus improving the accuracy and reliability of the annotation.
Especially with the advancement of gene expression technologies, new data have emerged not only on differentially expressed genes but also on underlying mechanisms of expression changes.
By combining nanodiscs and cell-free expression technologies, even completely detergent-free membrane protein characterization protocols can be designed.
When genome-wide expression technologies were introduced, they were heralded as a promising means through which biomarkers might be developed in a broad variety of diseases, including rheumatic disease such as rheumatoid arthritis and JIA36.
Inducible transgene expression technologies are of unmatched potential for biopharmaceutical manufacturing of unstable, growth-impairing and cytotoxic proteins as well as conditional metabolic engineering to improve desired cell phenotypes.
Conservative site‐specific recombination has been adapted for a multitude of uses, in both prokaryotes and eukaryotes, including genetic engineering, expression technologies, and as probes of chromosome structure and organization.
Thanks to advances in expression technologies over the past 25 years, many mammalian proteins can now be produced routinely in secreted form with yields in the gram/litre scale.
MH has a Ph.D. in Gene expression technologies.
In practice, the existence of correlation between data points acquired from gene expression technologies should be expected, and there is a need for accurate estimation of transcriptional states of genes under these conditions.
Development of cloning and expression technologies to produce recombinant proteins in prokaryotic and eukaryotic organisms enabled the production of numerous enzymes for diagnostic and industrial applications such as food, leather, textile or detergent industry (Kirk et al. 2002; Rai and Padh 2001).
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