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The major changes in gene expression take place during the early (day 3) and late (week 12) phases of HF feeding.
The expression patterns from the F50 samples differed considerably from the F100 and adult tissue, which suggests that changes in the global miRNA expression take place in brain between F50 and late F100 gestation.
Thus, large-scale and dynamic changes in gene expression take place throughout the first 48 hr of direct neuronal reprogramming.
Orchestrated changes in gene expression take place at the level of chromatin packaging which is regulated by enzymatic activity of epigenetic regulators that in turn affect histone modifications.
When activated by an agonist ligand in preadipocytes, a differentiation program is stimulated; in turn, morphological changes, lipid accumulation, and distinctive adipocyte gene expression take place [ 14– 17].
It may be the case that miRNA expression is maintained in healthy but senescent tissue and only during diseased states do perturbations in normal expression take place.
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At these stages, expression took place in arterioles covered with α-SMA-expressing mural cells and also in mural cell-free capillaries (data not shown).
We noticed that the polarized PDGFRα expression took place when at least one of the contact partner membranes expressed NG2, in agreement with data suggesting PDGFRα interacts with NG2 on surface membranes of cells.
The line between social expression and news increasingly gets blurred as this expression takes place.
Such is theater at the Sing Sing Correctional Facility: a series of paradoxes, in which freedom of creative expression takes place within the quite literal confines of prison walls.
The process of genetic expression takes place over several stages, and at each stage is the potential for further differentiation of cell types.
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