Integrated modeling revealed that certain strains are better suited to produce given compounds or express desired constructs considering native expression states of pathways that enable high-production phenotypes.
Northern blot expression profiles were displayed by three expression states as well as a bar chart, allowing for automated evaluation.
The right-hand side of the above expression states the expected net benefits when hospital i applies the standard treatment to all patients.
Thus, the left-hand side of the above expression states the net benefits hospital i gets when it applies personalized medicine.
The picture that emerges is that of a reciprocal relationship in which nuclear organization is not only shaped by gene expression states but also directly influences them.
This module has the intrinsic capacity to generate four distinct expression states, each characterized by the expression of a particular combination of pair-rule genes or expression mode.
Chromatin-based epigenetic inheritance cooperates with cis-acting DNA sequence information to propagate gene expression states and chromosome architecture across cell division cycles.
A plethora of recent reports has described multiple levels of chromosomal folding that can be related to gene-specific expression states.
As Frank La Rue, United Nations' Special Rapporteur on the promotion and protection of the right to freedom of opinion and expression, states, "the right to freedom of expression includes expression of views and opinions that offend, shock or disturb".
Remarkably, these expression states display a fluctuating equilibrium which parallels reversible histone modifications [7].
Rather, the unique gene structure of P1-mm itself may influence its variable expression states.
