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Genome wide gene expression profiles validated that ESC- and iPSC-derived osteoblasts resemble calvarial osteoblasts, and that Col2.3GFP expression serves as a marker for mature osteoblasts.
But why? Scientists have long believed that the wide-eyed facial expression serves as a social signal, showing those around us that we feel threatened.
This "physiologic" level of PIK3CA expression serves as an intracellular mediator maintaining tumor cell proliferation and growth by responding to extracellular growth factors.
In these studies gene expression serves as a common phenotype to recognize similar features in human cancers in vivo and to provide a direct linkage between the known biological perturbation and the clinical contexts [8] [12].
The quantification of intracytoplasmic WASp expression serves as a rapid and inexpensive screening test for WAS.
Gli1 expression serves as a readout for activation of the Shh signaling pathway.
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p38 MAPK expression served as control.
Given the tissue-specific differences we observed in transcriptomes, these data reinforce the idea that changes in gene expression serve as a primary mechanism underlying phenotypic plasticity.
This HEL24.3-OCT4-nEmGFP HEL24.3-OCT4-nEmGFP HEL24.3-OCT4-nEmGFP Ocellexpression, serving as a usefulineol to examine temporal changes in OCT4 expression in live cells during hiPSC culture, difaithfullyion and somatic cell reportsamming.
L19 expression served as internal control and was used to normalize for variances in input cDNA.
HKII expression served as a positive control for these experiments, and the data are presented in Figure S2A and B).
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