Sentence examples for expression selection from inspiring English sources

Codon usage bias is often correlated with genomic nucleotide composition bias but may also be correlated with gene expression, selection and drift [ 51, 52].

bBold genes are those identified by the microarray analysis, other genes were either not on the expression array or excluded by our gene expression selection criteria.

The threshold of gene expression selection was set to: FDR adjusted p-value <0.05, mapped reads >5, weighted proportions of fold change ≥ |2|, or unless otherwise clarified for more stringent analysis.

Thus, although the overall codon usage biased is determined by nucleotide composition mutation in T. thermophila, the presence of a preferred gene subset is under pressure from direct expression selection which probably results from the large effective population size of this species [ 49].

From Figure 6B, it can be seen that while the most T. thermophila P450 genes had ENc values slightly smaller than expected ones, the three genes with the significant high CAI values displayed a more biased codon usage according to the respective GC3s, indicating that they are probably under pressure from direct expression selection.

MESO924 and MESO428 cells with AKT1 and AKT2 shRNA stable expression (selection by puromycin for 10 days after infection) were plated at 3000 cells per well in a 96-well flat-bottomed plate and cultured for 24 h before being treated with BEZ235 (50 n M), RAD001 (20 n M), and U0126 (10  μ M).

Replating differentiating control cells after 3 days into 2i conditions with Rex1-expression selection gave very few AP-positive colonies, whereas Flcn knockdown cells yielded many.

The implementation techniques of GEP mainly include encoding scheme, K expressions, selection operator, mutation operator, insert string operation, gene inversion, restructuring operator, polygene chromosome and the contiguous function, the standard function set and users-defined functions based on the frequent function set, and fitness function selection (Table 2).

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ABCB1 appeared to be the only drug transporter which changed expression upon selection for paclitaxel resistance, whereas selection for docetaxel resistance also resulted in increased ABCC2 transporter expression ([X(4) = 10.038, p < 0.05]; Figure 3C).

In contrast, in the evolutionary runs selecting for medium expression, the selection window is essentially constant from round three through round five.