GCs and each of the intermediate stages leading to their formation are characterized by distinct morphologies and unique gene expression profiles, allowing experimental dissection of lineage progression in intact, developing organs (Lau and Bergmann, 2012; Pillitteri and Dong, 2013).
Moreover, we performed transcriptome expression profiling and identified differentially expressed genes located in the chalkiness-related QTL regions, providing valuable information for candidate gene verification and dissection of gene regulatory networks affecting rice grain appearance quality.
In this study, we have applied a functional genomics approach that combined gene expression profiling and computational molecular network analysis to obtain global dissection of the Snai2-dependent transcriptional response to DNA damage and to dissect the contribution of Snai2 on p53 target genes.
Microarray expression profiling of SCN infected root cells captured by laser assisted micro-dissection and root tissue at different time periods after inoculation were analyzed using the Genevestigator package [ www.genevestigator.com, [ 58, 59].
Marc Remke discussed further dissection of the molecular subtypes of medulloblastoma by using methylation and expression profiling on samples from the Medulloblastoma Advanced Genomic International Consortium MAGICC).
The analysis of multigene expression profiling is helpful to elucidate a series of medical and biological research questions including the dissection of basic biological processes [9], [10], the exploration of new drug targets [11], [12], [13], and the diagnosis of disease [14], [15], [16], [17].
The microchisel can also be used in the dissection of highly elastic nonfixed tissue, raising the possibility of using live cells for expression profiling.
RNA was procured by laser micro dissection of primary bladder tumors and corresponding lymph node metastases for Affymetrix U133 Plus 2.0 Gene Chip expression profiling.
Expression profiling, among the most widespread of the many uses of microarrays, has many applications which include the discovery of gene functions, pathway dissection, classification of clinical samples, and clustering analysis of genome-wide expression data from microarray hybridization.
Recombinant glucagon peptide expression profiling.
