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In this case, both subunits would have to be present for maximal inhibition of Kv12.2 channel expression on the membrane.
However, a subset of tumors of each of these ten cancer types showed high Ep-ICD membrane expression that correlated with high EpEx expression on the membrane detected using an Ep-CAM external domain (EpEx) specific antibody (MOC31), suggesting increased expression of the full length protein as detected by Ep-ICD and EpEx specific antibodies.
Human T cell blastoma cells (HSB2, ATCC, Manassas, VA) were stimulated with phorbol 12-myristate 13-acetate (PMA, Sigma-Aldrich, St . Louis MO) at 50 nM final concentration for 30 minutes (min) at 37°C to increase LFA-1 expression on the membrane.
It is possible that the progressive stabilization of the transferred CL3 TCR expression on the membrane of the transduced T cells might be due to a selection in culture of a limited set of T cell clones whose endogenous TCR is permissive for the expression of the exogenous one.
However, Cx43 expression on the membrane decreased after high glucose treatment).
PC-PLC inhibition resulted in enhanced HER2 internalization and lysosomal degradation, inducing downmodulation of HER2 expression on the membrane.
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Results suggest that TREM-1 expression on the membranes of neutrophils and monocytes in patients with septic syndrome is related to the type of infection.
As CD44 is a cell surface glycoprotein, we aimed at detecting its expression on the membranes of MDA-MB-231 cells after transfection by confocal laser microscope.
Cleavage of NKG2DL from the cell membrane is one way to reduce their expression on the plasma membrane leading to reduced susceptibility to NKG2D receptor-mediated cytotoxicity.
Combined with its expression on the basolateral membrane of hepatocytes [ 18], where urate is generated, the membrane potential would ensure that the SLC2A9-L isoform is responsible for transport of uric acid into the bloodstream [ 19].
We propose that pCMV6-rVegfr2 induced copious VEGFR2 protein expression on the cell membrane; however, the limited ability of the cell membrane to bind this protein allowed the excess release of receptor protein fragments into the culture medium.
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