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A negative effect of UPF1 and UPF2 expression on the host's anti-tumor response was observed (P<0.01).
These reports have also raised interesting questions relating to the impact of transient expression on the host and the possibility of mitigating this impact.
Therefore, using RNA-seq this study describes changes to the transcriptome of primary bovine cells following infection with Schmallenberg virus (SBV) or with a mutant lacking the non-structural protein NSs (SBVdelNSs) providing a detailed comparison of the effect of NSs expression on the host cell.
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We suggest that the regulatory effect of Alu transcription on the expression of the host genes may be one of the selective factors responsible for the frequent occurrence of Alu repeats in introns of human genes.
Taken together, these results suggest that the production of snoRNAs may be controlled by an unknown mTORC1-dependent mechanism that does not rely on the expression of the host genes.
These studies on symbiotic marine organisms provide evidence of the combined impact of symbionts and environmental factors on the mRNA expression of the host.
The loss of intronic miRNA from the host gene is possible if mutations are introduced into an intron without any effect on the function and expression of the host gene.
However, the efficient recruitment of neutrophils required TLR7 expression on both the host and bone-marrow-derived cells.
Given these circumstances, the working hypothesis for the present studies was: HERV-W env sequences responsible for encoding Syncytin-1 in the brain might be derived from multiple alleles and associated with neuroimmune gene expression depending on the host's age and health status.
The prominent counterpart to this latent gene expression pattern on the host's side was a significantly lower abundance of IL-2 transcripts, an increase in lymphocyte activation, as well as increase and decrease in apoptosis associated transcripts in lymphnodes of cattle with MCF as compared to the same tissue from healthy animals.
A small set of genes was identified showing differential expression depending on the host.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com