Sentence examples for expression of various molecules from inspiring English sources

On the other hand, sublethal levels of ROS can induce additional changes in DNA of tumor cells to make those cells malignant, stimulate the proliferation of cancer cells, and activate the expression of various molecules, some of which assist cancer cells to form metastatic colonies.

Using mRNA expression and correlation analyses, we designed the present study to elucidate (1) translocation of chemicals in inhaled f-PM to the heart, (2) induction of oxidative stress, one of the causes of cardiovascular diseases (CVDs), (3) mRNA expression related to CVDs, and (4) correlations among mRNA expression of various molecules and cardiovascular function.

NF-κB is an important transcription factor linked to many signal pathways, activating the expression of various molecules that mediate many biological events including cell survival.

TM-BBB4 cells retain the expression of various molecules and functions of the in vivo BBB [ 39].

A gate was set on conventional dendritic cells, which are CD11c high and B220 negative cells, and the surface expression of various molecules was examined.

Therefore, the differential expression of various molecules associated with ECM remodeling, particularly the MMPs provide specific targets to define their role in the regeneration process.

G1-S progression is regulated by the controlled expression and activity of various molecules such as Cyclins D, E and A, CDKs (CDK4, 6 and 2), CDKIs (INK4 and CIP/KIP family of proteins), Rb protein, and E2F transcription factors [27].

During LF hypertrophy, there are increases in the expression and activity of various molecules, including matrix metalloproteases (MMPs) [ 8– 10], tissue inhibitors of matrix metalloproteases (TIMPs) [ 11], platelet-derived growth factor-BB (PDGF-BB) [ 12], connective tissue growth factor (CTGF) [ 13], bone morphogenetic protein (BMP) [ 14], and inflammatory cytokines [ 15– 17].

A more detailed study involving molecular characterization of MSC from the synovial membrane by RT-PCR has revealed the expression of various matrix molecules, adhesion molecules, ligands, receptors and transcription factors [ 7].

Recent studies have suggested that a considerable number of genes coding for proteolytic enzymes are present within the E. histolytica genome and questions remain about the mode of expression of the various molecules.

Leukocyte-endothelium interactions require regulation of the expression of various adhesion molecules by endothelial cells, such as vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) [ 3].