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Genetic studies of shape in the mouse mandible found two recurrent patterns in environmental and genetic variation from different origins, suggesting that the development system 'channels' the phenotypic expression of variation in similar ways.
Under low Hsp90, predicted responses to selection of Hsp90-buffered traits increased with increased expression of variation.
It only seems logical, though, that changes in the regulation of mRNA molecules can lead to the expression of variation upon which selection acts.
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The images were captured at the same time of the year in order to minimise the expression of variations in such factors as light quality, geometry of the observation and variances in the state of a community over the course of a year (Mambo and Archer 2007).
The variation in GH dose needed to affect growth has previously been discussed in terms of misdiagnosis [ 23], but in recent years is more often seen as the expression of variations in individual responsiveness to GH [ 20, 24, 25].
It is generally accepted that chaperones control the expression of genetic variation as phenotypic variation by assisting in the folding of structurally unstable mutant proteins [33].
The table 'Expression in Blood' provides mean expression, coefficient of variation (CV) and EST based expression status ('H'/'M'/'W' for High/Medium/Weak).
Two indices are provided to assess variation in gene expression: 'coefficient of variation' (CV), and 'signal log ratio'.
We searched for genes with the least variability in expression (coefficient of variation ≤15%) and found 29.
The impact on expression profile of variation in the proportion of tumour cells and the nature of the non-tumour components have been largely unexplored.
Only 8% of the hypervariable genes, such as stress response or tissue specific genes with high values of gene expression coefficient of variation, were found to be body-methylated.
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